seiri.parvane@gmail.com
Academic Profile
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Educations
Title :
MicRNA and Breast Cancer
Work Experiences
Medical Laboratory Scientist
Research Assistant
Biochemistry Specialist
English Scores
TOEFL05-Mar-2022
101/120Total
Reading :
26/30
Listening :
26/30
Speaking :
25/30
Writing :
24/30
GRE General09-May-2022
307/340Total
Verbal Reasoning :
157/170
Quantitative Reasoning :
150/170
Analytical Writing :
3.5/6
Journal Publications
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microRNA‐141 is associated with hepatic steatosis by downregulating the sirtuin1/AMP‐activated protein kinase pathway in hepatocytesCorresponding author
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Micro‐RNAs as critical regulators of matrix metalloproteinases in cancerCorresponding author
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Micro‐RNAs as critical regulators of matrix metalloproteinases in cancer Somaye Noruzi, Mitra Azizian, Rezvan Mohammadi, Seyede Atefe Hosseini, Bahman Rashidi, Yousef Mohamadi, Abolfazl Nesaei, Parvaneh Seiri, Amirhossein Sahebkar, Reza Salarinia, Arad Mobasher Aghdam, Hamed Mirzaei Journal of cellular biochemistry 119 (11), 8694-8712, 2018 Metastasis is known to be one of the important factors associated with cancer‐related deaths worldwide. Several cellular and molecular targets are involved in the metastasis process. Among these targets, matrix metalloproteinases (MMPs) play central roles in promoting cancer metastasis. MMPs could contribute toward tumor growth, angiogenesis, migration, and invasion via degradation of the extracellular matrix and activation of pre‐pro–growth factors. Therefore, identification of various cellular and molecular pathways that affect MMPs could contribute toward a better understanding of the metastatic pathways involved in various tumors. Micro‐RNAs are important targets that could affect MMPs. Multiple lines of evidence have indicated that deregulation of various micro‐RNAs, including miR‐9, Let‐7, miR‐10b, and miR‐15b, affects metastasis of tumor cells via targeting MMPs. View at onlinelibrary.wiley.com Cited by 26 Related articles All 9 versions Factor Xa signaling contributes to the pathogenesis of inflammatory diseasesFirst author
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MicroRNA‐590‐3P suppresses cell survival and triggers breast cancer cell apoptosis via targeting sirtuin‐1 and deacetylation of p53Corresponding author
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Down-regulation of SIRT1 expression by mir-23b contributes to lipid accumulation in HepG2 cellsCorresponding author
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PPAR‐γ: Its ligand and its regulation by microRNAsFirst author
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Inhibition of sirtuin 1 deacetylase by miR-211-5p provides a mechanism for the induction of cell death in breast cancer cellsCorresponding author
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Research Keywords
cancer
Biology
Biochemistry
MicRNA