Sajjad Vakili-Samiani (MS, Hematology, Tabriz university of medical science, 2022) he took his comprehensive fields in Hematological malignancies target therapy with minor fields in Nanomedicine. His MSc thesis explored treating childhood Acute Lymphoblastic Leukemia (ALL) via selective targeting of WEE1 kinase as a treatment associated resistance factor. His current research focus on improvement of DNA damage based chemotheraputic agent's efficiency using specific immunoengineered and biocompatible nanoparticles. He is intrested in clinical research and clinical trial on ALL molecular target therapy to examine feasibility of his previous hypothesis.
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Wee1 kinase gene silencing by siRNA carried by TAT-CCMD Nanoparticle complex, could eliminate Doxorubicin resistance in Acute lymphoblastic leukemia.
Work Experiences
Laboratory technician
at Tabriz university of medi
Start : 19-Oct-2021
End : 28-Feb-2022
Journal Publications
Publication Title :
Increased susceptibility to doxorubicin-induced cell death in acute lymphocytic leukemia cells by inhibiting serine/threonine WEE1 kinase expression using the chitosan-carboxymethyl dextran-polyethylene glycol-TAT nanoparticlesSecond author